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Porter JB, Taher AT, Cappellini MD, Vichinsky EP

Drug companies have brought several to market as medications, including mainstay GLP-1 treatments for diabetes and weight loss

The possibility that oxidized forms of ascorbate play signalling roles cannot be discounted (Xu et al

Tumor angiogenesis leads to disordered internal tumor vasculature and aggravation of hypoxia, which in turn directly promotes the transcription of drug-resistance genes such as Multi-drug Resistance Protein1 ( MDR1 ), Multi-drug Resistant Associate Protein1 ( MRP1 ), and Breast Cancer Resistance Protein ( BRCP ) 4,5

Chen C, Ding Q, Shen B, Yu T, Wang H, Xu Y, et al

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