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The FDA has approved both drugs for chronic weight management for people diagnosed as obese or who are overweight with at least one weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol)

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Clin Cancer Res (2019) 25(20):606172

DHA is approved by the FDA for topical use

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Keep in mind that it also is well established in numerous veterinary journal articles that, for some breeds, LA/Ao ratios above 1.70 are normal, and in other breeds, ratios as low as 1.40 are enlarged