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617 HSK16149: HSK16149 is a novel ligand 2- subunit of VGCC

While most acute gastrointestinal toxicity is transient and can be managed with supportive care, a subset of patients experience serious symptoms, leading to discontinuation of the treatment

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The FDA notes the most severe adverse events include melanoma, posterior reversible encephalopathy syndrome, sympathomimetic toxidrome, and prolonged and painful boners

A structured titration plan helps minimise common side effects such as: Nausea Bloating Fatigue Digestive discomfort Even if a patient tolerated Ozempic well, that does not automatically mean starting weight loss injection Mounjaro at a higher dose is appropriate