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Possible Direct Mechanisms Although indirect effects dominate, GLP-1 receptors are expressed in reproductive tissues, suggesting potential direct roles: Ovarian Effects: Animal studies demonstrate GLP-1 receptor activation can influence granulosa cell function, increase cyclic adenosine monophosphate (cAMP), and modulate steroidogenesis

Berger, P.B

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These gene targets create powerful effects that researchers are particularly interested in especially how they translate into practical benefits for aging research

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2023: in press