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Unknown Effectiveness at Sub-Therapeutic Doses: Our understanding of tirzepatides effectiveness is based on evidence from trials using therapeutic doses of 2mg or more
It is also used to reduce the risk of major cardiovascular events in people with Type 2 diabetes and cardiovascular disease and lower the risk of worsening kidney disease in people with Type 2 diabetes and kidney disease
Some people also experience an impact on physical feelings of hunger and an impact on eating habits associated with reward (for example reduced pleasure in eating high-fat or sugary foods)
Antiepileptic Drugs (e.g., Phenytoin, Phenobarbital) Effect: May alter Vitamin B levels and reduce therapeutic effectiveness
Chiaramonte R, Sauro G, Giannandrea D, Limonta P, Casati L
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J Biol Chem 285:2355767
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