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Importantly, improved muSC activity translated not only to larger myofibers after injury but also to greater contractile function, with the peak torque of the [tibalis anterior] increased by 70% in NNMTi-treated mice compared to controls Readers of Living a Fully Optimized Life already know that this principle is critical to working your muscles to their fullest extent and by extension developing your physique to its maximum capacity
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Blocking IL-23 results in a downstream block of IL-22 and pathogenic Th17 cells involved in bone loss pathogenesis
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Importantly, controlled clinical trials directly measuring tendon/ligament healing, muscle repair and objective inflammatory biomarkers in humans are lacking, and most mechanistic insights still come from animal models
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